Authors:
Hina Saghir1 , Mariam Tariq2 , Asad Ali3 , Ambreen Zahoor4 , Farida Tahir5 , Waqar Ahmad6
1 Senior Registrar, Department of Medicine, Fazia Medical College, Air University, Islamabad
2 Assistant professor, Department of Medicine, HBS Medical and Dental Hospital, Islamabad
3 Registrar, Department of Medicine, HBS Medical and Dental Hospital, Islamabad
4 Associate professor, Department of Medicine, HBS Medical and Dental Hospital, Islamabad
5 Professor, Department of Medicine, HBS Medical and Dental Hospital, Islamabad
6 Professor, Department of Medicine, HBS Medical and Dental Hospital, Islamabad
Revisions:
Received: Aug 11, 2023 Revised: Nov 24, 2023 Accepted: Jan 05. 2024 Published: Jul 05, 2024
DOI: https://doi.org/10.70394/jhbsmdc.v4i1.41
Abstract
Enteric fever is a potentially fatal multisystem illness caused primarily by Salmonella typhi and, to a lesser extent, by Para typhi A, B, and C. Decades of indiscriminate usage of Antibiotics has led to emergence of multiple resistant strains. Multi drug resistant strains against Salmonella typhi has made treatment options limited and costly. According to WHO an estimated 11–20 million people get sick from typhoid all over the world. In the year 2022 an outbreak of Enteric fever emerged in April and spread all over Pakistan. This created a great concern as the causative organism were mostly Multi drug resistant. We recently have documented a case of extended drug resistant (XDR) Enteric Fever with a complicated clinical course, responding only to Carbapenem (Meropenem/Imipenem). The purpose of reporting this case was to highlight the morbidity, cost and therapeutic challenges which are associated with severe XDR S. typhi infection in Pakistan
Key words: Typhoid, COVID-19, Water Sanitation, Healthcare, Vaccine, Pakistan.
