Authors:
Shaista Ali1, Maryam Shan2 , Muhammad Amin3 , Shazia Muazzam4 , Maria Iram5
1 Professor, Department of Anatomy, HBS Medical & Dental College Islamabad
2 Department of Anatomy, Rawal Medical University
3 Department of Anatomy, Sahiwal Medical College, Sahiwal
4 Associate Professor, Department of Anatomy, HBS Medical & Dental College Islamabad
5 Department of Anatomy, Rawal Medical University
Revisions:
Received: Nov 19, 2023 Revised: Jan 14, 2024 Accepted: Feb 20, 2024 Published: Jul 05, 2024
DOI: https://doi.org/10.70394/jhbsmdc.v4i1.71
Abstract
Objective: To measure change in the thickness of calcified cartilage zone of male human articular cartilage (AC).
Methodology: Forty articular cartilage samples. were collected from the right knees of male cadavers aged between 21 to 60 years. The samples were placed in four groups. Tissue processing and cutting were followed by H&E staining. And calcified cartilage zone thickness was measured.
Results: With advancing age there was increase in thickness of articular cartilage at knee joint.
Conclusions: With advancing age, the calcified articular cartilage zone thickness increases leading to osteoarthritis. Delaying or preventing of this change with aging makes this zone an important target for preventive and therapeutic measures.
Key words: Articular Cartilage (AC), Calcified Cartilage Zone, Osteoarthritis
